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International journal in Gastroenterology and Hepatology
http://gut.bmjjournals.com
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Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines

Geneesmiddel:mesalazine , sulfasalazine
Auteurs:R A J Ransford and M J S Langman
Publicatie:Gut
Publicatiedatum:Gut 2002;51:536-539
Extra info:Spontaneous reports suggest that within the five sets of disorders considered, there is no evidence to indicate a safety advantage of mesalazine over sulphasalazine in the treatment of inflammatory bowel disease. Pancreatitis and interstitial nephritis appear significantly more common with mesalazine, and advice on renal monitoring in patients who receive mesalazine may need reinforcing.
Trefwoorden:pancreatitis, interstitiële nefritis, sulfasalzine
gut.bmjjournals.com/cgi/content/abstract/51/4/536? - 27 feb 2005

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